Much less is actually known regarding anti-PS/PT antibodies, apart from the elegant study of Oku et al. who showed that the expression of TF in procoagulant cells was induced by aPS/PT via p38MAPK phosphorylation, using both the IgG fractions from APS patients and a murine monoclonal aPS/PT antibody [15]. This evidence concerns the gene TF and autoimmune polyendocrinopathy.