For T2DM, RSV was revealed to alleviate cardiomyocyte inflammation, mitochondrial dysfunction, and metabolic disorders by downregulating tumor necrosis factor-α (TNF-α)/nuclear factor kappa B (NF-κB) signaling and by preventing palmitoyl-CoA (P-CoA) respiratory sensitivity in cardiomyocytes [30, 31]. This evidence concerns the gene TNF and type 2 diabetes mellitus.