ITIH4 and viral infectious disease: Carbohydrate-binding agents (CBA) may be able to block enveloped viruses other than HIV in their entry process and coronaviruses and influenza viruses are other examples of enveloped viruses that may be highly susceptible to the antiviral action of CBAs.In HIV, glycan deletions in gp120 delays the spread of virus.CBA administration may bring the viral infection under control before glycan deletions occur and the immune system can get involved in the further clearance of the virus.