In a previous study, we have already demonstrated in vitro the protective effect of Jojoba seed extracts against hyperglycemia-induced oxidative stress through the modulation of RINm5f beta cell cytotoxicity, generation of ROS, insulin release, caspase-3, activation, pro-oxidant and antioxidant defense, and status of the cells. The gene discussed is CASP3; the disease is Hyperglycemia.