In our series, we evidenced a progressive reduction of PTH and alkaline phosphatase during the first year after KT; hypercalcemia was observed during the first 3 months, with a low frequency at 1st year; hypophosphatemia showed predominance during the first 3 months, with remission at 1 year; hypovitaminosis was found in all KTRs, with a requirement of high doses of cholecalciferol and longer time for achieve normalization of 25OHD. The gene discussed is PTH; the disease is hypophosphatemia.