PTEN and melanoma: For example, the tumor suppressor gene PTEN has been demonstrated to compete for microRNAs shared with other transcripts, such as ZEB2, CNOT6L, VAPA, VCAN, in many types of cancer (e.g., glioblastoma, melanoma, prostate cancer, and breast cancer) (Tay et al., 2014; Poliseno and Pandolfi, 2015).