Some molecules, including extracellular signal-regulated kinase 1/2, arylhydrocarbon receptor, Histone h3, prostaglandin E receptor 2, nuclear factor κappa β (NF-κβ), programmed cell death 5, interleukin (IL)-36, IL-10, IL-4, Hypoxia Inducible Factor 1A, and arachidonate 15-lipoxygenase, are common molecular targets related to APR and RA, with the Eicosanoid signaling pathway the common pathway of APR and RA (Jia et al., 2015). Here, IL10 is linked to rheumatoid arthritis.