This woman presented with a Gitelman phenotype at the onset but was negative for mutations in SLC12A3. She presents with hypokalemia and hypocalciuria, asthenia, polydipsia, cramps, tingling, abdominal pain, polyuria, heart problems, tetany, hyperpyrexia, gastroesophageal reflux, recurrent proteinuria. The gene discussed is SLC12A3; the disease is asthenia.