Two enzymes related to ferroptotic lipid metabolism were found through the haploid gene screening of chronic myeloid leukemia cell line KBM7 cells: acyl-CoA synthetase (a long-chain family member 4 (ACSL4) for synthesizing Pes), and lysophosphatidylcholine acyltransferase 3 (LPCAT3) for lipid remodeling. Here, LPCAT3 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.