TRPC6 and Stroke: Resveratrol, neuroprotectin D1, and the main compound of green tea, (−)-epigallocatechin-3-gallate, inhibit calpain-mediated TRPC6 proteolysis and activate MEK/ERK or CaMKIV-dependent CREB pathways, therefore improving neurological status in experimental stroke (Lin et al., 2013a; Yao et al., 2013, 2014).