FHL2 and epilepsy: Although several studies have shed light on the relevance of FHL2 in terms of CNS-related pathology, including epilepsy and glioblastoma (Jamali et al., 2006; Kleiber et al., 2007; Li et al., 2008; Okamoto et al., 2013), the understanding of the regulatory role of FHL2 is yet to be fully appreciated.