Alternatively, the influence of FHL2 on dendritic modeling could be explained through interactions with the Wnt/β-catenin signaling pathway (Martin et al., 2002), which has been shown to refine dendrites in newborn DGCs (Kumamoto et al., 2012) and is also dysregulated in some forms of epilepsy (Hodges and Lugo, 2018). Here, FHL2 is linked to epilepsy.