CCNG1 and Familial prostate cancer: Previous researches have demonstrated that dysregulated CCNG1 mainly exerted a facilitator on various cancers, by promoting epithelial-to-mesenchymal transition (EMT) in esophageal squamous cell carcinoma [21], facilitating migration and invasion in ovarian cancer [19] and stimulating proliferation and metastasis in prostate cancer [26] and lung cancer [20].