These criteria would have missed 56% (14/25) of patients with PV in various genes (ATM (6), ATM/SDHA (1), BRCA2/ATM (1), BRCA2 (1), MSH2 (2), NBN (1), MITF (1), and CHEK2 (1)). The gene discussed is SDHA; the disease is acquired polycythemia vera.