24, 25 Based on these guidelines, healthy relatives carrying the familial ATM mutation, for example, who have a moderately to strongly increased risk for breast and a moderately increased risk for pancreatic cancer are eligible for consideration of publicly funded annual breast MRI screening starting at age 40 and annual pancreatic cancer screening with endoscopic ultrasound and alternating MRI of the pancreas beginning at age 50 (or 10 years before the youngest diagnosis of pancreatic cancer in the family). This evidence concerns the gene ATM and familial pancreatic carcinoma.