TMEM37 and infection: Two types of bioassays were performed to distinguish roles of 11 Pr1 proteases in sustaining insect pathogenicity and virulence-related cellular events after the fifth-instar larvae (~300 mg in body weight per capita) of the model insect Galleria mellonella were inoculated by topical application (immersion) of a 107 conidia/ml suspension for normal cuticle infection or intrahaemocoel injection of ~500 conidia per larva for cuticle-bypassing infection.