Considered more broadly, increases in CRP are associated with negative developments in a wide range of health situations, including infection [5], arthritis [6], surgery [7], intense exercise [8], sleep apnea [9], depression [10], air pollution [11], welding fume exposure [12], Parkinson's disease [13], pregnancy [14], inflammatory bowel disease [15], and various cancers [16], to name a few examples. The gene discussed is CRP; the disease is Parkinson disease.