Besides, the complex II‐dependent calcium retention capacity (CRC) and H2O2 production of liver mitochondria increased significantly at the early stage of type 1 diabetes (Figure S3F,J), yet complex I‐dependent membrane potential and CS activity in liver mitochondria were not affected (Figure S3H,L), and there were no significant differences of liver lipid accumulation in the early‐stage type 1 diabetic mice (Figure S3N,O). The gene discussed is CS; the disease is type 1 diabetes mellitus.