Meanwhile, hsa-miR-4284 was mainly enriched in pathways like morphine addiction (hsa05032; P value, 2.05E−03; gene, protein kinase C alpha (PRKCA)) and African trypanosomiasis (hsa05143; P value, 4.33E−03; gene, PRKCA). This evidence concerns the gene PRKCA and human African trypanosomiasis.