VAMP2 and schizophrenia: For example, miR-137 impaired vesicle release in a mouse model of schizophrenia [20]; miR-34c was reported mediate amyloid-beta (Aβ)-induced synaptic failure by targeting VAMP2 [21]; knockdown of miR-135a triggered an early stress response by disturbing presynaptic vesicle release [22]; miR-153 was found to be a contextual fear-induced miRNA in the dentate gyrus [23] and was reported to regulate vesicle release in zebrafish [24].