Both the percentages and absolute cell numbers of mDCs (Fig. 8a, b, c) and pDCs (Fig. 8d ,e, f) increased in IL-17 neutralized mice on day 3 p.i. compared with normal infection group (p < 0.05), and then mDCs and pDCs declined quickly to normal on day 5 p.i. (p < 0.05). The gene discussed is IL17A; the disease is infection.