As shown in Fig. 6, BAD, XLOC_397965, XLOC_2882304, XLOC_212066 and XLOC_108057 were upregulated in the adrenal glands of the MM sheep and PER3, SMAD1, TGFBR2 were downregulated in MM sheep. The gene discussed is TGFBR2; the disease is Miyoshi myopathy.