Naringin is the main active ingredient of total flavonoids ofRhizoma drynariae, which inhibit retinoic acid-induced osteoporosis in rats [15], increase bone morphogenetic protein (BMP)-2 expression, induce bone formation [16–18], and enhance the proliferation and osteogenic differentiation of human BMSCs in osteoporosis [19–21]. The gene discussed is BMP2; the disease is osteoporosis.