DMD and Duchenne muscular dystrophy: Next, we asked whether HC-AdV.eCas9gEX51 and HC-AdV.eCas9gIN43.gIN54 could, after transduction and subsequent differentiation of DMD patient-derived myoblasts, directly lead to the detection of Becker-like dystrophins in the resulting bulk muscle cell populations, i.e., without having to resort to additional experimental maneuvers, e.g., selecting DMD edited clones or enriching for sub-populations exposed to high RGN concentrations.