TSPO and Cognitive impairment: In another model, after applying permanent cortical ischemia by distal middle cerebral artery occlusion (dMCAO) in rats, the effects of the TSPO ligand 2-Cl-MGV-1 were assayed on poststroke cognitive deficits, neuronal damage, mitochondrial apoptosis, and secondary damage in the non-ischemic, i.e., indirectly affected ipsilateral thalamus and hippocampus, after this cortical infarction [172].