Reports about increased binding of 3H-PK11195, 18F-DPA-714, and 11C-SSR180575 in astrocytes in vivo also give encouragement regarding the diagnostic potential of TSPO for neuroinflammatory diseases [33,34], even despite the lack of a significant correlation between the binding of this TSPO PET tracer and 11C-Pittsburgh compound B (11C-PIB) to GFAP-positive astrocytes, as found in post-mortem tissue from patients with AD [35,36]. This evidence concerns the gene TSPO and Alzheimer disease.