PCSK9 and atrial fibrillation: A recent prospective study investigated PCSK9 levels in atrial fibrillation (AF) patients and revealed that high plasma levels of PCSK9 were significantly associated with urinary 11-dehydro-Thromboxane B2 (11-dh-TxB2), a marker of systemic COX1 activation, suggesting an interplay between PCSK9 and platelet activation [4].