Our data showed that the expression of MTDH was higher in the PBMCs of T-ALL patients than in the PBMCs of HCs (p < 0.05) (Fig. 2a, c), while CAY10526 (an inhibitor of mPGES-1) significantly inhibited MTDH expression (p < 0.05) (Fig. 2b, c) and PGE2 synthesis (p < 0.001) (Fig. 2d) in the PBMCs of T-ALL patients. The gene discussed is PTGES; the disease is acute lymphoblastic leukemia.