NMNAT1 and retinal degeneration: Familial mutations of NMNAT have been found to cause Leber congenital amaurosis 9 (LCA9) (Chiang et al., 2012; Falk et al., 2012; Koenekoop et al., 2012; Perrault et al., 2012) and retinal degeneration (Beirowski et al., 2008).