Administration of recombinant soluble human ACE-2 (rhACE-2) to capture SARS-COV-2 in the bloodstream may prevent its binding to lung cells, and enhance ACE-2 activity in lung tissue (Figure 1, panel A), which could be beneficial for COVID-19 patients with ARDS, possibly even at a late stage of the infection for patients in intensive care requiring assisted ventilation. Here, ACE2 is linked to COVID-19.