BRCA1 and neoplasm: The discrepancy could also be linked to the automated and continuous quantitation method used in our study to quantify the immune infiltrate of tumours, as scoring in the previous study was done manually and in a stratified manner.43 Furthermore, we did not assess the methylation in the gene coding region for BRCA1 and restricted our analysis to the identification of germline mutations in the BRCA1 and BRCA2 genes.