In this context, the objectives of the present study were 1) to describe the behaviour of circulating natriuretic peptides, namely BNP, NT-proBNP, MR-proANP, and sCD146 before and after PMC for severe MS, and 2) to investigate a potential role of these cardiovascular biomarkers to assess procedural success of PMC. The gene discussed is NPPB; the disease is myeloid sarcoma.