CD274 and neoplasm: In our analysis of the association between biological factors and the PD-L1 or PD-L2 expression on tumor cells and macrophages, only PD-L1 expression on macrophages was correlated with better prognostic factors (higher KPS and better MSKCC score in intratumoral macrophages, and lower proportion of LDH elevation in peritumoral macrophages).