Berberine hydrochloride inhibited proliferation and promoted apoptosis of NSCLC cells by suppression of the matrix metalloproteinase 2 (MMP‐2), Janus kinase 2 (Jak2)/vascular endothelial growth factor (VEGF)/nuclear factor κB (NF‐κB) regulatory axis.15 This evidence concerns the gene JAK2 and non-small cell lung carcinoma.