OTUD5 and cancer: To explore whether OTUD5 could exert its anti‐cancer effects on NSCLC via regulating PDCD5 expression, OTUD5 siRNA and the PDCD5 overexpressing plasmid were used to construct an si‐OTUD5/PDCD5 group, an si‐OTUD5 group, a PDCD5 group, and an si‐NC group, respectively.