The missense variant in SLC39A8 has previously been shown to be associated with multiple traits including alcohol intake, BMI, schizophrenia, Crohn's disease, lower brain grey matter volume and microbiome diversity;38,[56], [57], [58] we show for the first time a further novel association with higher diabetes and triglyceride levels, whilst highlighting variable effects on cholesterol levels. The gene discussed is SLC39A8; the disease is Crohn disease.