Univariate Cox model analysis revealed a statistically significant association between RFS and local invasion, lymph node metastasis, distant metastasis and 5-exolncRNAs panel, as well as between OS and age, local invasion, lymph node metastasis, distant metastasis, CEA, and 5-exolncRNAs panel. This evidence concerns the gene CEACAM5 and metastatic malignant neoplasm in the lymph nodes.