NFKBIA and diffuse large B-cell lymphoma: Moreover, the phosphorylation of IκBα was decreased concomitantly with the reduced intracellular amounts of linear polyubiquitin in HOIPIN-1-treated HBL1 cells (an ABC-DLBCL cell line), but not in BJAB cells (a GCB-DLBCL cell line) (Fig. 6f).