EDNRA and juvenile polyposis syndrome: PJI and nasal isolates did not differ in the prevalence of virulence genes (n = 101) except for etA, where seven of the nasal isolates carried genes encoding for this kind of exotoxin compared to none of the PJI isolates (p = 0.01), and lukD, where 47 of the 100 PJI isolates and 33 of the 100 nasal isolates carried the gene (p = 0.04) (Supplementary Table 5) No statistically significant differences in regulatory genes (n = 15) were found between the nasal and the PJI isolates, although agrII was found in 13 of the nasal and 26 of the PJI isolates (p = 0.06) (Supplementary Table 6).