In the ALS group, the level of IL-1 beta (p < 0.01), IL-6 (p < 0.01) and INF-gamma (p < 0.01) were significantly higher in comparison to controls whereas the anti-inflammatory cytokine IL-10 (p < 0.001) was significantly decreased (Fig. 4). This evidence concerns the gene IL6 and amyotrophic lateral sclerosis.