Our finding that peritoneal LPMs infiltrate early mouse ovarian cancer lesions indicate a resemblance to tumour-associated macrophages (TAMs) described in human ovarian tumours, which express high levels of mouse LPM-specific markers, including GATA-6, ADGRE1 (F4/80), TIMD4 and RXRα60. The gene discussed is ADGRE1; the disease is ovarian cancer.