CD4 and neoplasm: Additionally, we found high numbers of CD8+ T and CD4+ Th1 cells infiltrating into the tumor sites of patient TNBC#2 and relative to Treg cells, with patient TNBC#2 showing a 4-fold higher number of CD8+ T cells as compared with that in patient TNBC#1 and accompanied by the lowest expression of MHC class I genes, suggesting a higher accumulation of antigen-specific CTLs in patient TNBC#2 (Supplementary Figs. S3,S8).