In this respect, it is interesting that in both psoriasis and SLE the LL37-specific Th17-cells do exist and express Ror-ɣt but only in SLE, and not in psoriasis, they can express the TFH-markers Bcl-6 and high IL-21, at polyclonal and clonal levels. This evidence concerns the gene BCL6 and systemic lupus erythematosus.