CD44 and breast carcinoma: For instance, in a mice model, Yang, et al. 10 found that hyaluronic acid-modified IONSs containing CD44 antibodies were able to decrease the activity and volume of breast cancer tumors up to 2-fold via PTT (808 nm laser at 1 W/cm2) in addition to 40% enhancement of magnetic resonance imaging (MRI) of breast cancer tumors.