In this study, we found that an uncharacterized oncopeptide RBRP encoded by the previously annotated, uncharacterized lncRNA LINC00266-1 is significantly upregulated in cancers and strengthens the recognition and binding of the m6A reader IGF2BP1 to target mRNAs, such as c-Myc mRNA, to increase the stability and level of c-Myc mRNA, thereby promoting tumorigenesis. The gene discussed is IGF2BP1; the disease is cancer.