The expression of the WT RBRP or the IGF2BP1-binding-defective mutant RBRP G19A, which is resistant to the LINC00266-1 shRNA that targeted the 3′-UTR of the RBRP ORF, was restored in CRC cells with stable knockdown of LINC00266-1. This evidence concerns the gene IGF2BP1 and colorectal carcinoma.