ANKHD1 and Familial prostate cancer: Studies have demonstrated a role for ANKHD1 in promoting cell cycle progression/proliferation in renal, multiple myeloma and prostate cancer cells (Dhyani et al. 2012; Machado-Neto et al. 2014; Fragiadaki and Zeidler 2018) and in promoting hepatocellular carcinoma metastasis (Zhou et al. 2019).