Interestingly, seven of the shared significant genes have been associated to colorectal cancers, including UTP23 (Al-Tassan et al. 2015), GREM1 (Whiffin et al. 2014), SCG5 (COGENT Study et al. 2008), SMAD7 (Hofer et al. 2017), CABLES2 (Schmit et al. 2018), LAMA5 (Houlston et al. 2010), and PREX1 (Lu et al. 2019). This evidence concerns the gene SCG5 and colorectal cancer.