METTL3 and colorectal carcinoma: Single-sample GSEA (ssGSEA) [26] revealed that the gene sets related to Reactome_Glycolysis, Mootha_Glycolysis, Reactome_Glucose_Transport and KEGG_Glycolysis_Gluconeogenesis (glycolysis pathway) and Grade_Colon_And_Rectal_Cancer_Up (colorectal-carcinogenesis signature) were negatively correlated with METTL3-knockout CRC cells (Fig. 1h, Table S2).