Moreover, co-expression of PD-1/PD-L1, PD-1/PD-L1/PD-L2, and PD-1/LAG-3 was found to correlate with poor OS in AML patients with FLT3<sup>mut</sup>, RUNX1<sup>mut</sup>, and TET2<sup>mut</sup>, respectively. Here, TET2 is linked to acute myeloid leukemia.