NFKB1 and colorectal cancer: Buhrmann et al., [53] demonstrated that resveratrol modulates the TNF-β signaling pathway, induces apoptosis, suppresses NF-κB activation, epithelial-to-mesenchymal-transition (EMT), cancer stem cell-like cells formation and chemosensitizes colorectal cancer cells to 5-Fluorouracil in a tumor microenvironment.