CD40LG and infection: Among these, clinical and microbiological evaluation identified nine recent or active infections (phase 2 IgG ≥ 1:256 and phase 2 IgM: ≥1:48) and six possible recent or active infections (phase 2 IgG 1:128 and phase 2 IgM: ≥1:48), which leads to a community-level annual incidence rate of 25.7 per 100,000 inhabitants.