TTR and HP bound to fucose have been already proposed as a biomarkers of PDA [30,31]; CDH5 in pancreatic neuroendocrine tumors developed in Von Hippel–Lindau disease patients [32] and FCGBP in mucinous cysts in the pancreas [33] and PDA [34]. This evidence concerns the gene CDH5 and von Hippel-Lindau disease.