Moreover, Meng et al. [46] reported that tricin isolated from the methanol extract of young green barley (Hordeum vulgare L.)inhibited melanin biosynthesis and tyrosinase activity in B16/F10 melanoma cells through the hydroxyl group at the C-4’ position and methoxy groups at the C-3’,5’ positions of the tricin skeleton. Here, TYR is linked to melanoma.